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Baclofen (brand names Kemstro and Lioresal) is a derivative of gamma-aminobutyric acid (GABA). It is primarily used to treat spasticity and is under investigation for the treatment of alcoholism. It is an agonist specific to mammalian, but not fruit fly (Drosophila) GABAB receptors.Its beneficial effects in spasticity result from actions at spinal and supraspinal sites.
Birth defects which have been documented following Accutane exposure include abnormalities of the face, eyes, ears, skull, central nervous system, cardiovascular system, and thymus and parathyroid glands. Cases of IQ scores less than 85 with or without other abnormalities have been reported. There is an increased risk of spontaneous abortion, and premature births have been reported.

 

About one person in one hundred with hypertension has elevated levels of aldosterone; in these persons, the antihypertensive effect of spironolactone may exceed that of complex combined regimens of other antihypertensives. Due to its antiandrogen effect, it can also be used to treat hirsutism, and is a common component in hormone therapy for male-to-female transsexual and transgender people.
Flomax, Alna, Josir, Pradif, Secotex, Urolosin, Mecir (tamsulosin). Indicated for the treatment of Lower urinary tract Symptoms (LUTS) associated with benign prostate hyperplasia and available since 1996 as capsule controlled release formulation in the main world markets. Starting in 2005, a new tablet formulation based on the OCAS (Oral Controlled Absorption System) technology has been made available in many European markets and in Canada.

 

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